Punctures remain the most frequent inconvenience of a bike ride: at the moment there is no solid tire solution that solves all problems. The inserts inside the tire have brought safety but they are not to be seen as anti-puncture systems (read more about the topic).
The first distinction to make is: do I use inner tubes or tubeless? If you don't know, go and inform yourself immediately, otherwise click on one of these 2 links.
DRILLING WITH AIR CHAMBER
DRILLING WITH TUBELESS
I leave you the link to other interesting TUTORIALS.
